Status | Study |
Completed |
Study Name: L-leucine in Diamond Blackfan Anemia Patients Condition: Diamond Blackfan Anemia Date: 2015-02-18 Interventions: Drug: L-leucine L-leucine pills per os for 6 months |
Recruiting |
Study Name: Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies Condition: Sickle Cell Disease Transfusion Dependent Alpha- or Beta- Thalassemia Date: 2014-06-27 Interventions: Drug: Reduced Toxicity Ablative Regimen |
Recruiting |
Study Name: CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease Condition: Bone Marrow Failure Syndrome Severe Aplastic Anemia Severe Date: 2013-10-17 Interventions: Biological: CD34 Stem Cell Selection Therapy The CliniMacs (PLUS) Reagent System (Miltenyi CliniMacs CD3 |
Completed |
Study Name: Multi-Center Study of Iron Overload: Survey Study (MCSIO) Condition: Sickle Cell Disease Thalassemia Diam Date: 2013-07-30 |
Recruiting |
Study Name: Safety and Efficacy Study of Sotatercept in Adults With Transfusion Dependent Diamond Blackfan Anemia Condition: Diamond Blackfan Anemia Date: 2011-10-31 Interventions: Drug: Sotatercept |
Suspended |
Study Name: Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies Condition: Anemia, Sickle Cell Complex and Transfusion-dependent Hemoglobinopathies Date: 2011-08-16 Interventions: Biological: Enriched Hematopoetic Stem Cell Infusion Enriched Hematopoetic Stem Cell Infusion |
Active, not recruiting |
Study Name: Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia Condition: Diamond Blackfan Anemia Blackfan Diamond Date: 2011-05-20 Interventions: Drug: leucine Dosage of leucine will be dependent on body |
Suspended |
Study Name: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation Condition: Thalassemia Sickle Cell Disease Glanzmann Thrombasthenia Date: 2010-09-15 Interventions: Drug: Alefacept 0.25 mg/kg IV on day -40 and day -39 0.5 mg/kg IV on days -33, -26, -19 and -12 Alefacep |
Completed |
Study Name: Multi-Center Study of Iron Overload: Pilot Study Condition: Sickle Cell Disease Thalassemia Diam Date: 2010-04-30 |
Terminated |
Study Name: Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia Condition: Anemia Leukemia Acute Myeloid Leukemia (AML) Date: 2009-12-15 Interventions: Drug: Lenalidomide 2.5 mg/wk up to 5 mg 3x/wk Other |