Status | Study |
RECRUITING |
Study Name: Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN) Condition: Hemophilia B Date: 2023-10-27 Interventions: Adeno-associated viral vector carrying the FIX gene single infusion at dose 1. |
RECRUITING |
Study Name: An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX� in Patients With Hemophilia B Condition: Hemophilia B Date: 2023-08-15 Interventions: HEMGENIX is a gene therapy medicinal product that aims to deliver a factor IX (FIX) gene expression cassette to the liver of patients with hemophilia |
RECRUITING |
Study Name: Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs) Condition: Hemophilia B Date: 2023-08-01 Interventions: Administered as a single IV infusion. |
Completed |
Study Name: Efficacy and Safety of AlphaNine Versus BeneFIX in Patients With Severe Hereditary Haemophilia B Condition: Hemophilia B Date: 2017-03-16 Interventions: Drug: BeneFIX BeneFIX is a recombinant FIX that contains nonacog alfa, reconstituted in solvent and admi |
Recruiting |
Study Name: Long-Term Safety, Tolerability, and Efficacy of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia B Condition: Hemophilia B Date: 2016-11-21 |
Active, not recruiting |
Study Name: Safety and Dose Finding Study of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia B Condition: Hemophilia B Date: 2015-11-23 Interventions: Genetic: AAVrh10FIX non-replicating recombinant AAVrh10 encoding human FIX (hFIX) |
Recruiting |
Study Name: A Gene Therapy Study for Hemophilia B Condition: Hemophilia B Date: 2015-06-18 Interventions: Genetic: SPK-9001 A novel, bioengineered adeno-associated viral vector carrying human factor IX variant |
Active, not recruiting |
Study Name: Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia B Condition: Hemophilia B Date: 2015-03-04 Interventions: Genetic: AAV5-hFIX AAV5hFIX gene therapy Other Name: |
Withdrawn |
Study Name: Study of Recombinant Factor IX Product, IB1001, in Previously Treated Subjects With Hemophilia B Condition: Hemophilia B Date: 2013-11-14 Interventions: Biological: IB1001 Prophylaxis (during Treatment and Conti |
Active, not recruiting |
Study Name: Open-Label Single Ascending Dose of Adeno-associated Virus Serotype 8 Factor IX Gene Therapy in Adults With Hemophilia B Condition: Hemophilia B Date: 2012-08-27 Interventions: Biological: AskBio009 Single dose IV injection Other |