Status | Study |
Enrolling by invitation |
Study Name: Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy Condition: Osteoarthritis Osteoporosis Osteogenesis Imperfecta Date: 2016-05-16 Interventions: Device: spatially offset Raman spectrometer (SORS) Raman spectra will be collected non-invasively from p |
Active, not recruiting |
Study Name: A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome Condition: Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome Date: 2016-03-07 Interventions: Drug: KRN23 Doses may be titrated to achieve the target peak serum phosphorus range |
Completed |
Study Name: Maternal and Infant Vitamin Status During the First Nine Months of Infant Life Condition: Rickets Osteomalacia Osteopor Date: 2015-09-09 Interventions: Other: Blood and breastmilk samples The investigators collected maternal and infants blood samples from |
Active, not recruiting |
Study Name: Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH) Condition: X-linked Hypophosphatemia Date: 2015-08-25 Interventions: Biological: KRN23 KRN23 is a recombinant human immunoglobulin G isotype 1 (IgG1) monoclonal antibody (mA |
Completed |
Study Name: Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan Condition: Hypophosphatasia Date: 2015-08-11 Interventions: Biological: Asfotase Alfa Other Name: Strensiq |
Approved for marketing |
Study Name: Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP) Condition: Hypophosphatasia Date: 2015-07-08 Interventions: Biological: asfotase alfa Patients participating in this program will receive 6 mg/kg/week asfotase alfa |
Completed |
Study Name: Molecular Pathways Involved in the Pathogenesis and Behavior of Mesenchymal Phosphaturic Tumors Causing Oncogenic Osteomalacia Condition: Tumor Induced Oncogenic Osteomalacia Date: 2015-01-05 |
Active, not recruiting |
Study Name: Study of KRN23 in Adult Subjects With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS) Condition: Tumor Induced Osteomalacia (TIO) Epidermal Nevus Syndrome (ENS) Date: 2014-11-24 Interventions: Drug: KRN23 KRN23 is a recombinant fully human immunoglobulin G1 (IgG1) monoclonal antibody (mAb) that b |
Recruiting |
Study Name: Study of the Diagnostic Value of Stable Calcium Isotope Profiling in Bone and Calcium Disorders Condition: Bone Diseases Osteomalacia Os Date: 2014-09-22 |
Completed |
Study Name: Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09 Condition: Hypophosphatasia Bone Disease Date: 2014-09-05 Interventions: Biological: Retrospective Case Only |