Status | Study |
Completed |
Study Name: An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects Condition: Orphan Cholestatic Liver Diseases Progressive Familial Intrahepatic Ch Date: 2017-02-27 Interventions: Drug: 3 mg [14C]-A4250 capsule Each subject will receive a single administration of 3 mg [14C]-A4250 cap |
Completed |
Study Name: A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384 Condition: Orphan Cholestatic Liver Diseases Primary Biliary Cirrhosis Date: 2016-11-01 Interventions: Drug: A4250 Drug: CRC (A3384) |
Completed |
Study Name: Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease Condition: Alagille Syndrome Progressive Familial Intrahepatic Cholestasis Date: 2014-05-01 |
Temporarily not available |
Study Name: Expanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler Disease Condition: Byler Disease Date: 2014-03-19 Interventions: Drug: RAVICTI open label expanded access protocol of titrated dosing regimen of RAVICTI for up to 60 wee |
Active, not recruiting |
Study Name: Open Label Study to Evaluate Efficacy and Long Term Safety of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Progressive Familial Intrahepatic Cholestasis Condition: Progressive Familial Intrahepatic Cholestasis (PFIC) Date: 2014-02-05 Interventions: Drug: LUM001 LUM001 oral dose |
No longer available |
Study Name: Transition From Buphenyl to RAVICTI for the Therapy of Byler Disease Condition: Byler Disease Date: 2013-09-20 Interventions: Drug: Glycerol phenylbutyrate Other Name: RAVICTI |
No longer available |
Study Name: Buphenyl Therapy for Byler's Disease Condition: Byler Disease Date: 2013-02-04 Interventions: Drug: Buphenyl |
Completed |
Study Name: Sulfation of Bile Acids as a Biomarker for Hepatobiliary Diseases Condition: Hepatobiliary Diseases Date: 2010-08-31 |
Recruiting |
Study Name: Evaluating the Genetic Causes and Progression of Cholestatic Liver Diseases (LOGIC) Condition: Liver Diseases Alagille Syndrome Alpha 1-Antitrypsin Defic Date: 2007-12-07 |