Clinical Trial: Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Intermediate Risk of Mortality

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Randomized, Multi-Center, Event-Driven Trial of TAVI Versus SAVR in Patients With Symptomatic Severe Aortic Valve Stenosis and Intermediate Risk of Mortality, as Assessed

Brief Summary: Randomized controlled, multi-center trial randomizing patients with symptomatic severe aortic stenosis at intermediate operative risk of mortality, as assessed by the STS-PROM-Score, in a 1:1 fashion to transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR) to test, whether TAVI is non-inferior to SAVR regarding short and long-term mortality (1 and 5 year).