Clinical Trial: Research Interest Antiphospholipid in Predicting Embolic Risk During Infective Endocarditis

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational




Official Title: Research Interest Antiphospholipid in Predicting Embolic Risk During Infective Endocarditis

Brief Summary:

EMBOL-EI (Research Interest antiphospholipid antibody for embolic risk prediction in infective endocarditis) is a prospective cohort study with a biological collection.

The main objective is: to re-evaluate the potential value of antiphospholipid (aPL) antibodies as predictors of embolic events in IE in the light of the improved current knowledge on these aPL.

The seconds objectives are: Other plasma biomarkers of hemostasis (coagulation activation markers: D-dimer fragment 1 + 2 of prothrombin; endothelial biomarkers: plasma levels of von Willebrand factor) will be taken into account in the analysis, and interest in predicting embolic risk, alone or in combination with aPL will be investigated.