Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: ANK-dependent ATP Efflux Causes Calcium Pyrophosphate Deposition in Cartilage
Brief Summary: This study will investigate the hypothesis that probenecid, a medication currently used for gout, reduces levels of ATP in the joint fluid of patients with calcium pyrophosphate deposition disease (CPPD), another common type of crystal-related arthritis. There is good evidence that CPPD results from an excess of ATP in joints. The investigators will measure levels of ATP in joint fluid before and after 5 days of treatment with probenecid. This study will serve to rationalize larger studies of probenecid in CPPD.