Clinical Trial: Long-term Outcomes of Chronic Hepatitis C Patients Post Sofosbuvir-based Treatment

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational



Official Title: Long-term Hepatic and Extra-hepatic Outcomes of Chronic Hepatitis C Patients Post Sofosbuvir-based Interferon-free Treatment (LONGHEAD Study)

Brief Summary:

Primary Objective:

To evaluate the long-term outcomes including liver related morbidity, mortality and hepatocellular carcinoma (HCC) development as compared to those of historical control with interferon(IFN)-based treatment.

Secondary Objective:

  1. To access liver fibrosis progression/regression in CHC patients after sofosbuvir-based treatment.
  2. To investigate the long-term outcomes of extrahepatic manifestations of the sofosbuvir-based treated cohort as compared to their pretreatment status.