Clinical Trial: Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational




Official Title: Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.

Brief Summary: Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature. The condition can be difficult to separate from adipositas in general. Screening for hypercortisolism in adults has been easier the last years, because we can measure free cortisol in saliva samples at late night. In children we still dont have reference ranges for saliva cortisol in children, so the screening is still troublesome, based on Collection of 24-hour urine.The meaning of this study is to establish reference ranges for saliva cortisol, and evaluate in a cohort with adipose children if screening with saliva cortisol is sensitive and specific enough to be the New screening test for hypercortisolism in children too.