Study Status: COMPLETED
Recruit Status: COMPLETED
Study Type: OBSERVATIONAL
Official Title: CD4+CD25+High FOXp3+ Regulatory T Cell With Related Interleukins and Vitamin D-binding Protein in Periodontal Disease Progression : Synergy or Cocaphony
Brief Summary: T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need.
The role of Treg and related cytokines in succession of periodontal inflammation is recently a subject of research interest.
Chronic gingivitis and periodontitis being chronic inflammatory diseases can upregulate various cytokines in the systemic circulation and gingival crevicular fluid.
This study aimed to compare levels of Tregs with Interleukin-21, 22, 33, 35 and vitamin D-binding protein in blood and GCF of periodontally healthy persons, chronic gingivitis patients, and severe chronic periodontitis patients.