Clinical Trial: Xyrem and Brain Dopamine in Narcolepsy

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Does Xyrem Influence Brain Dopamine in Patients With Narcolepsy? A PET Imaging Investigation

Brief Summary:

The overall aim is to establish whether the drug Xyrem® has an action on the brain dopamine system in patients with narcolepsy.

Trial Objective is to establish, using positron emission tomography (PET), in Xyrem®-naïve narcolepsy with cataplexy patients, whether a single dose of Xyrem® causes changes in striatal binding of 11C-raclopride and 11C-DTBZ that would suggest altered activity of brain dopamine neurones.