Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: A Phase I Study of Intralesional Administration of an Adenovirus Vector Expressing the HSV-1 Thymidine Kinase Gene (AdV.RSV-TK) in Combination With Escalating Doses of Ganciclovir in Patients With Cut
Brief Summary:
RATIONALE: Inserting a modified herpesvirus gene into a person's melanoma cells may make the cancer more sensitive to the antiviral agent ganciclovir.
PURPOSE: Phase I trial to study the effectiveness of gene therapy in treating patients who have stage IV melanoma.