Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: A Phase I Clinical Trial to Determine the Safety and Immunogenicity of the Candidate Mycobacterium Avium Subspecies Paratuberculosis (MAP) Vaccine ChAdOx2 HAV in Healthy A
Brief Summary:
A phase I dose escalation study to assess the safety and immunogenicity of the candidate vaccine ChAdOx2 HAV in healthy volunteers.
Volunteers will be recruited and vaccinated in Oxford, England.
All vaccinations will be administered intramuscularly. Three different doses will be tested (5x10^9 vp, 2.5x10^10 vp and 5x10^10vp).
The total duration of the study will be 52 weeks from the day of enrolment for all volunteers.