Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Pediatric Obesity Observational Prospective Trial: Microbiome and Metabolism During Obesity Target Therapeutics
Brief Summary: Using an observational case-control cohort design, the investigator aims to define the mechanisms underlying microbiome regulation of metabolism in adolescence before and after medically indicated therapies for obesity. The investigator's overarching hypothesis is that gut bacteria control host weight, insulin sensitivity, and response to weight-loss treatments by modifying host metabolism.