Research Article: Serum Mac-2 binding protein glycosylation isomer and galectin-3 levels in adult-onset Stills disease and their association with cytokines
Abstract
Background: Autoinflammation with cytokine dysregulation may be implicated in the pathophysiology of adult-onset Stills disease (AOSD); however, the relationship between galectins and cytokines in patients with active AOSD remains unknown. We aimed to examine the relationship between circulating cytokines/chemokines and galectin-3 (Gal-3) or its ligand, Mac-2 binding protein glycosylation isomer (M2BPGi), in Japanese patients with AOSD.
