Research Article: Beneficial Effect of Oral Sildenafil Therapy on Childhood Pulmonary Arterial Hypertension
Abstract
Background Pulmonary arterial hypertension (PAH) is a progressive and fatal disease. Sildenafil is a type 5 phosphodiesterase inhibitor and pulmonary vasodilator. Therefore, we hypothesized that sildenafil would improve distance walked in 6 minutes and hemodynamics in children with PAH.
